PureStem®

PureStem® ES-101 Progenitor expresses transthyretin (TTR), a marker of Blood Brain Barrier cells and choroid plexus making this progenitor valuable for research into diseases related to Cerebral Spinal Fluid or Alzheimer’s disease where defective choroid plexus function has been hypothesized. Learn More

PureStem® ES-139 Progenitor expresses tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18), heart and neural crest derivatives expressed 2 (HAND2), RNU2, GPR116, SPINK1, KRT86, GABRB1 (gamma-aminobutyric acid (GABA) A receptor, beta 1), and INS-IGF insulin- insulin-like growth factor 2. Learn More

PureStem® ES-154 Progenitor expresses the markers of intermediate mesodermal progenitors of the kidney (Lusis et al, 2010) including: Wilms tumor 1 gene (WT1), nephronectin (NPNT), TSHZ2, SIX1, and distal HOX gene expression HOXA4, B8, C8. Learn More

PureStem® ES-198 Progenitor expresses heparan sulfate 6-O-sulfotransferase 2 (HS6ST2), KIT, the ion channel SLC24A3, EPHA5, HEY2, and PLCH2. Learn More

Natural killer cell receptor proteins; expresses: cystatin SN (CST1), killer cell lectin-like receptor subfamily C, member 2 and 3 (KLRC2 and KLRC3). Expresses phosphodiesterase 5A, cGMP-specific (PDE5A), neuronal cell adhesion molecule (NRCAM), forkhead box G1 (FOXG1), and GATA binding protein 3 (GATA3). This progenitor does not express HOX genes. Learn More

PureStem® ES-209, Meso-prx/latp Progenitor expresses markers of intermediate mesoderm particularly resembling early renal progenitors, metanephric mesenchyme and S-shaped body markers (PAX2, PAX8, LHX1, HNF1B and JAG1). Learn More

This clonal human embryonic progenitor line expresses markers of brain and nervous system related cells (TTR, ZIC2,TH,NES). Learn More

PureStem® ES-236 Progenitor expresses markers of dopamine metabolism and sympathoblastic neural crest including the neurotrophin receptor NTRK, TH, CRABP1, KIT. Learn More

PureStem Progenitor ES-263 expresses the markers: UGT2B17, SLITRK1, peripherin (PRPH), and ATP-binding cassette, sub-family G (WHITE), member 1 (ABCG1). The most distal HOX gene expression is HOXC6. Learn More