Stem Cell Reprogramming
Comprehensive portfolio of reagents for cellular reprogramming
Cellular reprogramming has transformed the field of stem cell biology and created a new source of pluripotent cells for research, drug discovery, and regenerative medicine therapies. Scientists have made huge strides since the breakthrough publications in 2006 describing the first methods to generate induced pluripotent stem (iPS) cells.
Today, many different technologies exist to reprogram somatic cells including chemical methods. ESI BIO offers small molecules and antibodies that are widely used in high impact studies to assist in cellular reprogramming and the targeting of key pathways in stem cell experiments.
Now available: BioLite™ antibodies for live cell identification

Small Molecules
Small molecules have become powerful tools in the reprogramming process and are playing an exciting role in the development of novel reprogramming techniques. The use of small molecules allow researchers to accurately and specifically regulate metabolic pathways and promote epigenetic modifications with specific regulatory and temporal control over normally complex experiments.
ESI BIO offers a collection of small molecules in convenient formats that enable definitive and reproducible control mechanisms for stem cell biology and reprogramming protocols.
Antibodies
The ability to characterize stem cell populations and to monitor the dynamic changes in gene expression that occur during reprogramming and differentiation is an essential part of all stem cell research. When generating iPS cell lines, early identification of pluripotent colonies can save considerable time and effort. Manually picking colonies based on morphology alone is not always reliable.
BioLite™ antibodies allow for direct immunofluorescent staining of live, unfixed, pluripotent stem cell populations and aid in selecting reprogrammed colonies confirmed by marker expression.
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Product List:
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Thiazovivin, 2 mg
SKU: ST10015Highly selective ROCK inhibitor Learn More$249.00 -
SP600125, 5 mg
SKU: ST10025Novel and selective JNK inhibitor. Learn More$57.00 -
SB431542
SKU: Multiple SKUS - View Products OptionsPotent, selective inhibitor of TGF-βRI, ALK-4, ALK-5, and ALK-7. Learn MoreStarting at: $95.00
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RG108, 5 mg
SKU: ST10027DNA methyltransferase inhibitor Learn More$87.00 -
RepSox, 5 mg
SKU: ST10021Selective inhibitor of TGF-β type I receptor ALK5 Learn More$78.00 -
PD173074, 2 mg
SKU: ST10034FGFR1 inhibitor Learn More$72.00 -
PD0325901
SKU: Multiple SKUS - View Products OptionsPotent inhibitor of MEK1/2. Learn MoreStarting at: $125.00
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CHIR99021
SKU: Multiple SKUS - View Products OptionsHighly selective GSK-3 inhibitor. Learn MoreStarting at: $112.00
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BIX01294, 2 mg
SKU: ST10030Inhibits G9a histone methyltransferase Learn More$82.00 -
BioLite™ TRA-1-81 (DyLight 488) anti-Human Antibody, 100 μL
SKU: ST11008Detects TRA-1-81 expression in live, unfixed pluripotent stem cell populations by immunofluorescent staining. Learn More$270.00