ESIBIO

  (877) 636-4978

Purmorphamine, 5 mg

Be the first to review this product

Purmorphamine is a small molecule that promotes the differentiation of human and murine mesenchymal progenitor cells into osteoblasts.
SKU: ST10011
$145.00
 

Order Offline:

T: 877.636.4978
E: orders@esibio.com

F: 510.648.3255

 

Description

Details

Purmorphamine is a small molecule that promotes the differentiation of human and murine mesenchymal progenitor cells into osteoblasts. The mechanism of action study of Purmorphamine indicates that it is an agonist of Smoothened, a 7-transmembrane receptor of the hedgehog signaling pathway. Purmorphamine can also be used to replace sonic hedgehog for the generation of motor neurons from human embryonic stem cells.

Details

Details

Product Overview  
Molecular Weight 520.62
Molecular Formula C31H32N6O2
Chemical Name 2-(1-Naphthoxy)-6-(4-morpholinoanilino)- 9-cyclohexylpurine
CAS Number 483367-10-8
PubChem Identifier 5284329
Appearance Off-white solid
Alternative Names Shh Signaling Antagonist VI
Preparation & Storage   
Solubility Soluble in DMSO at 50 mm
Reconstitution For powder form, reconstitute in DMSO to the desired concentration. For detailed instructions on reconstitution and use in cell culture please reference product data sheet.
Storage and Stability Solid: Shipped at room temperature. Store at -20°C. Stable for 6 months when stored as directed.
References 1. Li XJ, et al. (2008) Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules. Stem Cells 26: 886-893. PMID: 18238853. 2. Wu X, et al. (2004) Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. Chem Biol 11: 1229-1238. PMID: 15380183.

Reviews

Write Your Own Review

You're reviewing: Purmorphamine, 5 mg

Tags

Tags

Use spaces to separate tags. Use single quotes (') for phrases.