Description
Details
Details
Details
Molecular Weight | 465.34 |
---|---|
Molecular Formula | C22H18Cl2N8 |
Chemical Name | 6-[2-[4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino]ethylamino]pyridine-3-carbonitrile |
CAS Number | 252917-06-9 |
PubChem Identifier | 9956119 |
Purity | >97% by HPLC analysis |
Alternative Names | CT99021, GSK-3 Inhibitor XVI |
Solubility | Soluble in DMSO at 100 mM |
Reconstitution | For powder form, reconstitute in DMSO to the desired concentration. For detailed instructions on reconstitution and use in cell culture please reference technical data sheet. |
Storage and Stability | Solid: Shipped at room temperature. Store at -20°C. Stable for 6 months when stored as directed. 10 mM Solution: Shipped on dry ice. Store at -20°C. Avoid repeated freeze-thaw cycles. Stable for 6 months when stored as directed. |
References | Li, W., et al. (2009) Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Stem Cells 27: 2992-3000. PMID: 19839055. Ring, D.B., et al. (2003) Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 52: 588-595. PMID: 12606497. Ying, Q., et al. (2008) The ground state of embryonic stem cell self-renewal. Nature 453: 519-523. PMID: 18497825. |
Technical Documents |