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PureStem® ES-199 Progenitor expresses cystatin SN (CST1), killer cell lectin-like receptor subfamily C, member 2 (KLRC2), KLRC3,
phosphodiesterase 5A, cGMP-specific (PDE5A), neuronal cell adhesion molecule (NRCAM), forkhead box G1 (FOXG1), and GATA binding protein
3 (GATA3). This progenitor does not express HOX genes.
Upon differentiation in micro-mass culture with TGFβ3, PureStem Progenitor ES-199 up-regulates MYH11 and tachykinin 3 (neuromedin K, neurokinin beta) (TAC3).
PureStem Progenitor ES-199 was derived from the registered parental hES cell line H9 (WA09) as described (West, M.D. et al, 2008)
PureStem Progenitor ES-199 was derived from the registered parental hES cell line H9 (WA09) as described (West, M.D. et al, 2008)
Details
Details
| Quality Control | This line is negative for HIV (1, 2), HBV, HCV, bacteria, mycoplasma, and fungal contamination. Certificates of analysis are available on request. |
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| Technical Documents | ES-199 Technical Data Sheet |
| References | West MD, et al. (2008) The ACTCellerate initiative: large-scale combinatorial cloning of novel human embryonic stem cell derivatives. Regen Med. 3(3):287-308. PMID: 18462054 |
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