Description
Details
PureStem® ES-198 Progenitor expresses heparan sulfate 6-O-sulfotransferase 2 (HS6ST2), KIT, the ion channel SLC24A3, EPHA5, HEY2, and PLCH2. The most distal HOX gene expression is HOXC6. Differentiation in high density culture with bFGF induces the up-regulation of the osteoclast-association receptor (OSCAR). PureStem ES-198 Progenitor was derived from the parental hES cell line WA09 as described (West, M.D. et al, 2008).
Propagation Potential
PureStem Progenitor ES-198, is sold at passage 12 (the original clonal isolate confluent in a 1.9 cm2 well was P1), which corresponds to approximately 13.5 doublings since the first 1.9 cm2 well and approximately 31.5 doublings since its original clonal plating.
Propagation Potential
PureStem Progenitor ES-198, is sold at passage 12 (the original clonal isolate confluent in a 1.9 cm2 well was P1), which corresponds to approximately 13.5 doublings since the first 1.9 cm2 well and approximately 31.5 doublings since its original clonal plating.
Details
Details
| Quality Control | This line is negative for HIV (1, 2), HBV, HCV, bacteria, mycoplasma, and fungal contamination. Certificates of analysis are available on request. |
|---|---|
| Technical Documents | ES-198 Technical Data Sheet |
| References | West MD, et al. (2008) The ACTCellerate initiative: large-scale combinatorial cloning of novel human embryonic stem cell derivatives. Regen Med. 3(3):287-308. PMID: 18462054 |