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PureStem® Progenitor Cells

PureStem cell lines are human embryonic stem cell-derived clonal embryonic progenitors. As such, they display a regenerative (pre-fetal) pattern of gene expression such as the absence of COX7A1 expression and are useful in applied research in Induced Tissue Regeneration (iTR™).PureStem progenitors feature unique and phenotypically distinct embryonic progenitors representing early germ layers including ectoderm, mesoderm, neural Crest and endoderm. Progenitors express functional or gene expression differentiated phenotypes when cultured In PureStem Differentiation Kits; including mesenchymal epithelial myogenic and neurogenic phenotypes. Many PureStem progenitors generate unique differentiated cells and tissues by following known cell fates, including chondrogenic, osteogenic, endothelial and epithelial cell fates. PureStem progenitors are clonally pure and highly characterized with gene expression profiles both in their undifferentiated and differentiated fates. They do not express telomerase, and offer substantial proliferative capacity.

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  • PureStem® ES-199 Progenitor

    SKU: ES-199
    Natural killer cell receptor proteins; expresses: cystatin SN (CST1), killer cell lectin-like receptor subfamily C, member 2 and 3 (KLRC2 and KLRC3). Expresses phosphodiesterase 5A, cGMP-specific (PDE5A), neuronal cell adhesion molecule (NRCAM), forkhead box G1 (FOXG1), and GATA binding protein 3 (GATA3). This progenitor does not express HOX genes. Learn More
    $495.00

  • PureStem® ES-198 Progenitor

    SKU: ES-198
    PureStem® ES-198 Progenitor expresses heparan sulfate 6-O-sulfotransferase 2 (HS6ST2), KIT, the ion channel SLC24A3, EPHA5, HEY2, and PLCH2. Learn More
    $495.00

  • PureStem® ES-154 Progenitor

    SKU: ES-154
    PureStem® ES-154 Progenitor expresses the markers of intermediate mesodermal progenitors of the kidney (Lusis et al, 2010) including: Wilms tumor 1 gene (WT1), nephronectin (NPNT), TSHZ2, SIX1, and distal HOX gene expression HOXA4, B8, C8. Learn More
    $495.00

  • PureStem® ES-139 Progenitor

    SKU: ES-139
    PureStem® ES-139 Progenitor expresses tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18), heart and neural crest derivatives expressed 2 (HAND2), RNU2, GPR116, SPINK1, KRT86, GABRB1 (gamma-aminobutyric acid (GABA) A receptor, beta 1), and INS-IGF insulin- insulin-like growth factor 2. Learn More
    $495.00

  • PureStem® ES-101 Progenitor

    SKU: ES-101
    PureStem® ES-101 Progenitor expresses transthyretin (TTR), a marker of Blood Brain Barrier cells and choroid plexus making this progenitor valuable for research into diseases related to Cerebral Spinal Fluid or Alzheimer’s disease where defective choroid plexus function has been hypothesized. Learn More
    $495.00

  • PureStem® ES-1001 GDF11+ Progenitor

    SKU: ES-1001
    PureStem® ES-1001 GDF11+ Progenitor expresses the NKD2, HAND2, TBX3, FOXF1, and the HOX genes: HOXA10 and the relatively distal HOX genes HOXB7 and HOXC8 as well as the hindlimb marker PITX1 (expressed in hindlimb, but not forelimb bud mesenchyme). Learn More
    $950.00

  • PureStem® EN7 Progenitor

    SKU: ES-184
    PureStem® EN7 Progenitor expresses neurofilament, medium polypeptide (NEFM), RGS1, tyrosine hydroxylase (TH), sarcosin (KBTBD10), gamma-aminobutyric acid (GABA) A receptor, beta 1 (GABRB1) (useful in screening for psychoactive drugs including those for the treatment of schizophrenia), the tight junction protein CLDN5, and MASP1. Learn More
    $495.00

  • PureStem® E72 BETATROPHIN+ Progenitor

    SKU: ES-100
    PureStem® E72 BETATROPHIN+ Progenitor expresses the Mohawk homeobox gene (MKX), HAND2, TBX15, and the HOX genes: HOXA10, HOXD11 (implicated in forelimb development), but does not express the lateral plate mesoderm marker HOXB6 unless exposed to retinoic acid. Learn More
    $950.00

  • PureStem® E-44 Progenitor

    SKU: ES-170
    PureStem® E-44 Progenitor expresses CST1, CST2 (cystatins; proteinase inhibitors found in saliva, tears and seminal fluid) and STATH in its undifferentiated form. Learn More
    $495.00

  • PureStem® Choroid Plexus Differentiation Kit

    SKU: EM-2006
    Optimal differentiation kit for PureStem® ES-210, Ecto-ntu Progenitor. Learn More
    $295.00

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