ESIBIO

  (877) 636-4978

PEGDA

Be the first to review this product

Polyethylene (glycol) Diacrylate (PEGDA) is a blank slate hydrogel that gels rapidly at room temperature in the presence of a photo-initiator and UV light. They are hydrophilic, elastic and can be customized to include a variety of biological molecules.
Product Name SKU Price Qty
PEGDA, 1 g GS700
$105.00
PEGDA, 5 g GS705
$500.00
PEGDA, 1 mL GS711
$55.00
 

Order Offline:

T: 877.636.4978
E: orders@esibio.com

F: 510.648.3255

 

Description

Details

Polyethylene (glycol) Diacrylate (PEGDA) hydrogels are powerful tools for uncovering basic cellular biology because they are considered biologically inert (“blank slate”) and their mechanical properties can be varied over a large range of moduli. PEGDA is an emerging scaffold for tissue engineering and regenerative medicine since polymerization can occur rapidly at room temperature and requires low energy input, has high water content, is elastic, and can be customized to include a variety of biological molecules. PEGDA is a crosslinker repeating polymer crosslinker. >95% acrylated. Can be used as a thiol-reactive crosslinker in our HyStem systems at low concentration, or can be used to make a PEGDA-only hydrogel in the presence of a free-radical chain photoinitiator and a UV light source. PEG-only gels do not typically support cell attachment without the incorporation of cellular attachment sites.

Applications
Regular and 3-D cell culture
Tissue engineering
Photolithography

Details

Details

Technical Documents Technical Data Sheet
References Salinas CN and Anseth KS, The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities. Biomaterials. (2008) 29:2370-7.

Kloxin AM, et al.Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties Science (2009) 324, 59.

DeForest CA, Polizzotti BD, and Anseth KS, Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments Nat. Mater. (2009) 8: pp. 659-664.

Baird IS, Yau AY, and Mann BK, Mammalian cell-seeded hydrogel microarrays printed via dip-pin technology BioTech. (2008) 44:249-256.

Baek TJ et al, Photolithographic Fabrication of Poly(Ethylene Glycol) Microstructures for Hydrogel-based Microreactors and Spatially Addressed Microarrays J. Microbiol. Biotechnol. (2007) 17: 1826-1832.

Taite LJ, Rowland ML, Ruffino KA, Smith BR, Lawrence MB, West JL. Bioactive hydrogel substrates: probing leukocyte receptor-ligand interactions in parallel plate flow chamber studies. Ann Biomed Eng. (2006) 34:1705-11.

Du Y, Lo E, Ali S, Khademhosseini A. Directed assembly of cell-laden microgels for fabrication of 3D tissue constructs. Proc Natl Acad Sci U S A. (2008) 105:9522-7.

Khademhosseini A, Yeh J, Jon S, Eng G, Suh KY, Burdick JA, Langer R. Molded polyethylene glycol microstructures for capturing cells within microfluidic channels. Lab Chip. (2004) 4:425-30.

Liao H, Munoz-Pinto D, Qu X, Hou Y, Grunlan MA, Hahn MS. Influence of hydrogel mechanical properties and mesh size on vocal fold fibroblast extracellular matrix production and phenotype. Acta Biomater. (2008) 4:1161-71.

Patel PN, Smith CK, Patrick CW Jr. Rheological and recovery properties of poly(ethylene glycol) diacrylate hydrogels and human adipose tissue.J Biomed Mater Res A. (2005) 73:313-9.

Panda P et al, Stop-Flow Lithography to Generate Cell-Laden Microgel Particles. Lab Chip (2008) 8:1056-1061.

Ma PX and Elisseeff J editors, Scaffolds in Tissue Engineering, CRC Press Boca Raton, FL 2006.

Reviews

Write Your Own Review

You're reviewing: PEGDA

Tags

Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

You may also be interested in the following product(s)